Search results for "mass [excited state]"
showing 10 items of 5250 documents
Antikonvulsiva, 1. Mitt. Thiocarbamoylbutyroguanamine
1986
Durch Anlagerung von Butyroguanamin (1) an die Isothiocyanate 2a-c sind die Thiocarbamoylbutyroguanamine 3a-c zuganglich. Auf dem Wege der Acylierung von 3 sind unsymmetrisch substituierte Butyroguanamine 4 erhaltlich. Unter den neu entwickelten Verbindungen zeichnet sich insbesondere 3c durch antikonvulsive, fungizide und die Magensauresekretion hemmende Wirkungen aus. Anticonvulsivic Agents, I: Thiocarbamoylbutyroguanamines The thiocarbamoylbutyroguanamines 3a-c are accessible by addition of butyroguanamine (1) to the isothiocyanates 2a-c. Unsymmetrically substituted butyroguanamines 4 are obtainable by acylation of 3. Among the newly prepared compounds, 3c in particular exhibits anticonv…
Verschiedenartige Additionsreaktionen von 2-Cyano-2-propylradikalen an p-Tolylmethacrylat und 4-Cyclohexylphenylmethacrylat
1976
Durch Umsetzung von p-Tolylmethacrylat oder 4-Cyclohexylphenylmethacrylat in stark verdunnter, siedender Benzollosung mit einem sehr grosen Uberschus an 2,2′-Azoisobutyronitril wurden die erwarteten Additionsprodukte mit 2-Cyano-2-propylradikalen (1) erhalten, namlich p-Tolyl- bzw. 4-Cyclohexylphenyl-[4-cyano-2-(2-cyano-2-propyl)-2,4-dimethyl]valerianat (3a bzw. 3b) mit rund 50% Ausbeute. Daneben wurden p-Tolyl- bzw. 4-Cyclohexylphenyl-(4-cyano-4-methyl-2-methylen)valerianat (4a bzw. 4b), p-Tolyl- bzw. 4-Cyclohexylphenyl-[4-cyano-2(2-cyano-2-methyl-1-propyl)-4-methyl]valerianat (5a bzw. 5b), p-Tolyl- bzw. 4-Cyclohexylphenyl-(4-cyano-2,4-dimethyl)valerianat (6a bzw. 6b) und p-Tolyl- bzw. 4-C…
Comparison between a guaiac and three immunochemical faecal occult blood tests in screening for colorectal cancer
2012
Abstract Background The aim of this study was to compare the performance of the guaiac-based faecal occult blood test (G-FOBT), with that of three immunochemical faecal occult blood tests (I-FOBT) which allow automatic interpretation. Patients and methods Under the French organised screening programme, 85,149 average-risk individuals aged 50–74 participating in the third screening round, performed both the G-FOBT (Hemoccult-II test) and one of the I-FOBTs: FOB-Gold, Magstream and OC-Sensor. Results Given the chosen threshold, the positivity ratio between the different I-FOBTs and the G-FOBT was 2.4 for FOB-Gold, 2.0 for Magstream and 2.2 for OC-Sensor (P = 0.17). The three I-FOBTs were supe…
Synthetic indicator of the impact of colorectal cancer screening programmes on incidence rates
2020
ObjectiveThe impact of a screening programme on colorectal cancer (CRC) incidence in its target population depends on several variables, including coverage with invitations, participation rate, positivity rate of the screening test, compliance with an invitation to second-level assessment and endoscopists’ sensitivity. We propose a synthetic indicator that may account for all the variables influencing the potential impact of a screening programme on CRC incidence.DesignWe defined the ‘rate of advanced adenoma on the target population’ (AA-TAP) as the rate of patients who received a diagnosis of advanced adenoma within a screening programme, divided by the programme target population. We com…
Comparison of the yield from two faecal immunochemical tests at identical cutoff concentrations – a randomized trial in Latvia
2016
OBJECTIVE We have compared the performance of two faecal immunochemical tests (FIT) in an average-risk population. MATERIALS AND METHODS Altogether, 10 000 individuals aged 50-74 were selected randomly from the population of Latvia in 2011 and assigned randomly either to OC-Sensor or to FOB Gold single-time testing. Positivity of the test, frequency of colonic lesions, number needed to screen (NNscreen) and scope for the detection of an advanced neoplasm (cancer and advanced adenoma) were compared between the tests using the same cutoff concentrations in µg/g faeces. Confidence intervals (CIs) at 95% were calculated. RESULTS Positivity with the cutoff set at 10 µg/g faeces was 12.8% (95% CI…
NOseq: amplicon sequencing evaluation method for RNA m6A sites after chemical deamination
2020
Abstract Methods for the detection of m6A by RNA-Seq technologies are increasingly sought after. We here present NOseq, a method to detect m6A residues in defined amplicons by virtue of their resistance to chemical deamination, effected by nitrous acid. Partial deamination in NOseq affects all exocyclic amino groups present in nucleobases and thus also changes sequence information. The method uses a mapping algorithm specifically adapted to the sequence degeneration caused by deamination events. Thus, m6A sites with partial modification levels of ∼50% were detected in defined amplicons, and this threshold can be lowered to ∼10% by combination with m6A immunoprecipitation. NOseq faithfully d…
Healthy and unhealthy eating after a behaviour change intervention in primary care
2022
Abstract Background: To prevent and reduce non-communicable diseases, the Norwegian Directorate of Health encourages Healthy Life Centres (HLCs) in all municipalities. Aims: This study investigates whether the behaviour change interventions at HLCs positively affected participants’ diet and to evaluate predictors for healthy and unhealthy eating. Our data are part of the Norwegian Healthy Life Centre Study, a 6-month, pragmatic randomised controlled trial (RCT). Methods: Totally, 118 participants ≥18 years old were randomised to an intervention group (n 57), or a waiting list (control group) (n 61). Eighty-six participants met at the 6 months follow-up visit. We merged the participants to o…
Adsorptionseffekte als Fehlerquellen bei Lichtzerstreuungsmessungen
1956
Es werden die Einflusse der Adsorption von Hochpolymeren aus den Losungen auf Lichtzerstreuungsmessungen untersucht. Zunachst wird die Adsorption aus Losung an Glaswolle und Glaspulver in verschiedenen Losungsmitteln gemessen. Es zeigt sich, das sowohl Konzentrationserniedrigung, bestimmt im Differentialrefraktometer, wie auch eine Abnahme des Molekulargewichtes, aus der Lichtzerstreuung bestimmt, infolge selektiver Adsorption auftreten. Beim Schutteln der Losungen tritt als weiterer Effekt ein Abbau der Kettenmolekule ein. Beim Filtrieren von Losungen nehmen durch Adsorption im Filter Konzentration und Molekulargewicht ab. Die Abnahme wachst mit der Feinheit des Filters, d. h. mit seiner O…
Characterization of NOM
2015
Worldwide reports over the last few decades have shown that the amount of natural organic matter (NOM) in surface water is continuously increasing, which has an adverse effect on drinking water purification. For many practical and hygienic reasons, the presence of NOM in drinking water is undesirable. Various technologies have been proposed for NOM removal with varying degrees of success. The properties and amount of NOM, however, can significantly affect the process efficiency. To improve and optimize these processes, it is essential to characterize and quantify NOM at various points during purification and treatment. It is also important to be able to understand and predict the reactivity…
Study of Selective Adsorption of Gases by Calorimetry
2013
This chapter is devoted to the study of coadsorption of gases in nanoporous solids by using the differential calorimetry. In the first part, the thermodynamic principles of adsorption of gases are recalled. Some of them have already presented in chapter one. However a special attention has been paid here to the determination of the adsorption enthalpies and entropies and we focused on the selective adsorption of binary mixtures. Then the specific experimental technique based on the combination of differential calorimetry with manometry and gas phase chromatography or mass spectrometry is shown in details. In the last part, the thermodynamic concepts on coadsorption are illustrated with expe…